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ld information  (Genomics England)

 
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    Genomics England ld information
    Ld Information, supplied by Genomics England, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ld information/product/Genomics England
    Average 86 stars, based on 1 article reviews
    ld information - by Bioz Stars, 2026-06
    86/100 stars

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    reference identifiers additional information other ld columns 130 042 901 miltenyi biotec other cd4  (Miltenyi Biotec)
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    Miltenyi Biotec reference identifiers additional information other ld columns 130 042 901 miltenyi biotec other cd4
    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, <t>CD4+</t> T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page
    Reference Identifiers Additional Information Other Ld Columns 130 042 901 Miltenyi Biotec Other Cd4, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ld information  (Genomics England)
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    Genomics England ld information
    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, <t>CD4+</t> T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page
    Ld Information, supplied by Genomics England, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, <t>CD4+</t> T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page
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    linkage disequilibrium ld block information  (Thermo Fisher)
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    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, <t>CD4+</t> T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page
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    Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page

    Journal: eLife

    Article Title: Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

    doi: 10.7554/elife.69975

    Figure Lengend Snippet: Figure 6. PERK signaling drives b-selected thymocyte apoptosis in Sel1l CKO mouse. (A and B) Representative images of thymus (A) and quantification of total thymocytes, DP, SP4 and SP8 thymocytes (B) from age (6-week-old) and gender-matched control (Ctrl, Sel1lflox/flox), Sel1l KO (Sel1lflox/flox; CD2- iCre), Perk KO (Perkflox/flox; CD2-iCre)and Sel1l/Perk double knockout (DKO. Sel1lflox/flox, Perkflox/flox; CD2-iCre) mice. n = 3–5 each group. (C and D) Representative images of spleen (C) and quantification of total splenocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (D) from the same mice with indicated genotype as in A and B. n = 3–5 each group. (E and F) Representative images of the inguinal (left) lymph node (E) and quantification of total lymphocytes, total CD3+ T cells, CD4+ T cells, and CD8+ T cells (F) from the same mice with indicated genotype as in A and B. n = 3–5 each Figure 6 continued on next page

    Article Snippet: DOI: https://doi.org/10.7554/eLife.69975 36 of 37 Appendix 1—key resources table continued Reagent type (species) or resource Designation Source or reference Identifiers Additional information Other LD Columns 130-042-901 Miltenyi Biotec Other CD4 (L3T4) MicroBeads, mouse 1 x 2 mL 130-117-043 Miltenyi Biotec Other CD8a (Ly-2) MicroBeads, mouse 130-117-044 Miltenyi Biotec Other DAPI (4’,6- Diamidino-2Phenylindole, Dihydrochloride) D1306 Thermo Fisher Other Precision Count Beads 424902 Biolegend Other RBC Lysis Buffer (10X) 420301 Biolegend Other Liquid DAB+ K3468 Dako Liu, Yu, Xu, et al. eLife 2021;10:e69975.

    Techniques: Control, Double Knockout